GLP-3R
GLP-3R
GLP-3R is a next-generation single-molecule triple agonist (retatrutide) that simultaneously activates the GIP, GLP-1, and glucagon receptors, three key regulators of appetite, insulin secretion, and energy expenditure. This unified incretin approach both suppresses appetite and increases metabolic rate, distinguishing it from single- and dual-receptor agonists. In a 48-week Phase 2 clinical trial, the compound produced mean weight reductions of up to 24.2% of body weight, among the largest reported for a pharmacological agent, with a 17.5% mean reduction reached by 24 weeks. Research also shows substantial improvements in glycemic control, hepatic fat (with many participants achieving resolution of liver steatosis), blood pressure, and lipid profiles. The glucagon component uniquely boosts energy expenditure and fat oxidation, while the GLP-1 and GIP components drive appetite regulation and insulin sensitivity. These findings make retatrutide a leading model compound in metabolic, obesity, glucose-regulation, and hepatic-steatosis research.
For laboratory and research use only. Not for human consumption.
Frequently Asked Questions
Are your products third-party tested?
Yes. Every batch is independently tested for identity and purity by HPLC and mass spectrometry at U.S. accredited labs, and a Certificate of Analysis is available for each batch.
What purity can I expect?
All compounds are 99%+ purity, verified by HPLC.
How should this be stored?
Store lyophilized (freeze-dried) material cool and dry; refrigerate once reconstituted. Refer to the product details for compound-specific guidance.
How fast do you ship?
Orders generally ship within 1–2 business days in temperature-controlled, tamper-evident packaging with tracking.
Are these safe for human use?
No. All products are sold strictly for in-vitro research and laboratory use only and are not for human or animal consumption.
Reconstitution Calculator
Enter your vial size, the amount of bacteriostatic water you are adding, and your target dose to see the concentration and how many units to draw on a U-100 insulin syringe.
For in-vitro research and laboratory reference only. Not medical advice. Products are not for human or animal consumption. Calculations assume a standard U-100 insulin syringe (100 units = 1 mL).