NAD+
NAD+
NAD+ (nicotinamide adenine dinucleotide) is an essential coenzyme present in every living cell, central to energy metabolism, mitochondrial function, and DNA repair. It shuttles electrons in the reactions that generate cellular ATP and serves as the required substrate for sirtuins and PARP enzymes that govern DNA repair, gene expression, and stress responses. Research shows NAD+ levels decline substantially with age, by up to 50% between young adulthood and middle age, driven in part by rising CD38 activity, contributing to mitochondrial dysfunction and reduced cellular resilience. Studies demonstrate that restoring NAD+ reactivates sirtuin signaling, improves mitochondrial efficiency, and enhances DNA-repair capacity in aged models. Declining NAD+ is closely linked to hallmarks of aging, metabolic decline, and neurodegeneration. As the master cofactor connecting metabolism to longevity pathways, NAD+ is one of the most extensively studied model compounds in aging, mitochondrial, and cellular-energy research.
For laboratory and research use only. Not for human consumption.
Frequently Asked Questions
Are your products third-party tested?
Yes. Every batch is independently tested for identity and purity by HPLC and mass spectrometry at U.S. accredited labs, and a Certificate of Analysis is available for each batch.
What purity can I expect?
All compounds are 99%+ purity, verified by HPLC.
How should this be stored?
Store lyophilized (freeze-dried) material cool and dry; refrigerate once reconstituted. Refer to the product details for compound-specific guidance.
How fast do you ship?
Orders generally ship within 1–2 business days in temperature-controlled, tamper-evident packaging with tracking.
Are these safe for human use?
No. All products are sold strictly for in-vitro research and laboratory use only and are not for human or animal consumption.
Reconstitution Calculator
Enter your vial size, the amount of bacteriostatic water you are adding, and your target dose to see the concentration and how many units to draw on a U-100 insulin syringe.
For in-vitro research and laboratory reference only. Not medical advice. Products are not for human or animal consumption. Calculations assume a standard U-100 insulin syringe (100 units = 1 mL).